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Nanomedical Engineering Lab.

Welcome! This lab is focusing on the medical field, related to diagnosis and treatment using multifunctional nanomaterials.

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Research

본 연구실의 연구 주제는 

다양한 기능의 나노물질을 이용하여

바이오메디컬 분야로 응용하고자 하는 것입니다. 

대표적으로, 조기진단을 위한 바이오센서와

효과적인 질병의 치료를 위한 약물전달 시스템을 개발하고자 하며,

세부적인 연구주제는 다음과 같습니다.

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1. 엑소좀 안의 마이크로RNA 측정을 위한 나노 프로브 개발

2. 나노물질을 이용한 바이러스 DNA/RNA 측정

3. 약물 스크리닝 플랫폼 개발

4. 크리스퍼 유전자가위 기술 기반의 암 진단 및 치료

​

Our research interests are based on the biomedical field application, including early diagnosis and efficient therapy by using multifunctional nanomaterials.

Detailed research topics at present are below:

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1. Development of nanobio sensing probe and platform for exosomal miRNA detection.

2. Viral DNA & RNA detection system by nanomaterials.

3. In vitro drug screening platform with nanobio system. 

4. CRISPR-based nanotherapeutics for cancer treatment. 

Latest Publications

CRISPR-Cas12a based nucleic acid amplification-free DNA biosensor via Au nanoparticle-assisted metal-enhanced fluorescence and colorimetric analysis

A CRISPR-Cas12a-assisted cell-free DNA (cfDNA) detection method was developed by using double-strand and single-strand DNA (dsDNA and ssDNA)-functionalized Au nanoparticles. Notably, this proposed method exhibited sensitivities that reached the femtomolar level without nucleic acid amplification. Both colorimetric and metal-enhanced fluorescence analysis can be exploited for the intuitive and sensitive measurement of target DNA within 30 min. 

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